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[Signs of the Times] Signs of the Times News for Wed, 21 Jan 2009: Adamantanes fight influenza by inhibiting the function of a protein called the membrane ion channel, or the M2 protein. According to the computational comparison of the avian flu genomes, upwards of one-third of the strains contained a key mutation that changed the M2 protein in a way that allowed the virus to escape the inhibiting effects of adamantanes.

[Project Disaster] Carnivores at risk for H5N1”¦..as evidenced by disease found in red ...: High titers were also detected in internal organs of 10-week-old chickens and in highly susceptible species of wild swans, geese, and ducks that were experimentally infected with a clade 2.2 HPAI virus (H5N1), e.g., whooper swans, mute swans (Cygnus olor), bar-headed geese (Anser indicus), common pochards (Aythya ferina), and tufted ducks (Aythya fuligula) (30-32). For example, virus titers in internal organs of common pochards and tufted ducks infected with a low dose of clade 2.2 HPAI virus (H5N1) reached >106 TCID50/mL (32).

[PeripheralsPerspective's Weblog] H5N1 AND YOU: As focus is placed on the world’s economy and markets, the World Health Organization and the Centers for Disease Control and Prevention are investigating and issuing alerts regarding the Confirmed Cases of Avian Influenza A (H5N1). In an assessment of the current situation, the following is stated: “The highly pathogenic avian influenza A (H5N1) epizootic (animal outbreak) in Asia, Europe, the Near East, and Africa is not expected to diminish significantly in the short term.

[A Pandemic Chronicle] Hong Kong crow positive for H5N1: Flublogia has long decried the dangers presented by improper disposal of poultry with confirmed or suspected infection of highly pathogenic H5N1, an issue that is manifestly more dangerous when an infected flock is not known or suspected to be so when biosecurity measures may not be a priority.

[The FASEB Journal Research Communications] Structure of the influenza virus A H5N1 nucleoprotein ...: We also used our crystal structure to build a ring-shaped assembly of nine NP subunits to model the miniribonucleoprotein particle previously visualized by electron microscopy. Our study of H5N1 NP provides insight into the oligomerization interface and the RNA-binding groove, which are attractive drug targets, and it identifies the epitopes that might be used for universal vaccine development.—Ng, A.

[The Congress Blog] From Global Crisis to “Global Government”: In discussing the rise of the emerging powers, particularly China and India, the report observes that their economic progress has been “achieved with an economic model that is at odds with the West’s traditional laissez faire recipe for economic development.” So the question is, “whether the new players - and their alternative approaches - can be melded with the traditional Western ones to form a cohesive international system able to tackle the increasing number of transnational issues.” It continues, saying that “the national interests of the emerging powers are diverse enough, and their dependence on globalization compelling enough, that there appears little chance of an alternative bloc forming among them to directly confront the more established Western order. The existing international organizations - such as the UN, WTO, IMF, and World Bank - may prove sufficiently responsive and adaptive to accommodate the views of emerging powers, but whether the emerging powers will be given - or will want - additional power and responsibilities is a separate question.”[24] So, as the new powers emerge, as a result of Western elite-directed globalization, they will likely merge with the Western controlled world order as opposed to becoming an alternative or opposition force to it.

[Effect Measure] Effect Measure : Today is bird flu's birthday: The extreme move, which follows a ban on chicken imports from China, was announced Sunday by Hong Kong Director of Health Margaret Chan after doctors confirmed at least 12 cases of the H5N1 virus, four of which were fatal. Nine other people, ranging widely in age, are suspected of having the virus, a particularly virulent type previously believed to infect only birds.

[The Ohio State University - Home page Events] Study: Excessive Use Of Antiviral Drugs Could Aid Deadly Flu: So far, avian flu, the H5N1 strain of the influenza A virus, has been restricted to fewer than 400 human cases worldwide, but the virus’s presence in birds has led to culling of large populations of infected species. Experts believe that to date, the avian flu can be transmitted to humans only from diseased birds.

[Prepared Citizens] Cease and Desist All Experimentation On Children « Prepared Citizens: Eleven outbreaks of H5N1 were reported worldwide in June 2008 in five countries (China, Egypt, Indonesia, Pakistan and Vietnam) compared to 65 outbreaks in June 2006 and 55 in June 2007.

Reflected tags on Technorati: Blog, H5n1, Bird Flu Monitor