Bird Flu Monitor > Edmund’s Blog » Avian Flu Becoming More Resistant to Antiviral Drugs

[Edmund's Blog] Researchers using Google Earth technology are able to visually chart individual outbreaks of the avian flu as it has spread outward from China over the past decade, including gene mutations that are causing a resistance to a major class of antiviral drugs.

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[Untitled] Avian Influenza: Avian Flu Turning More Resistant To Antiviral ...: Avian Flu Turning More Resistant To Antiviral Drugs. eMaxHealth.com -- The avian flu, an Influenza A subtype dubbed H5N1, is evolving a resistance to a group of antiviral drugs known as adamantanes.

[Untitled] Avian Flu Becoming More Resistant To Antiviral Drugs, University ...: University of Colorado -- A new University of Colorado at Boulder study shows the resistance of the avian flu virus to a major class of antiviral drugs is increasing through positive evolutionary selection, with researchers documenting the trend in more than 30 percent of the samples tested.

[Untitled] Avian flu becoming more resistant to antiviral drugs, says ...: The avian flu, an Influenza A subtype dubbed H5N1, is evolving a resistance to a group of antiviral drugs known as adamantanes, one of two classes of antiviral drugs used to prevent and treat flu symptoms, said CU-Boulder doctoral student Andrew Hill, lead study author. The rise of resistance to adamantanes -- which include the nonprescription drugs amantadine and rimantadane -- appears to be linked to Chinese farmers adding the drugs to chicken feed as a flu preventative, according to a 2008 paper by researchers from China Agricultural University, said Hill.

[Untitled] Colorado Arts & Sciences Magazine » Avian flu resisting antiviral ...: First detected in China in 1996, the avian flu has spread throughout Asia and to India, Russia, Pakistan, the Middle East, Africa and Europe by various carriers, including poultry and migratory waterfowl, Hill said. While H5N1 is not highly communicable to humans from birds or between humans, experts are concerned future evolution of this subtype or other subtypes, or genetic re-assortment between subtypes, could make an avian influenza strain more contagious with the potential to cause a pandemic.

[Untitled] Avian flu becoming more resistant to antiviral drugs, says ...: The avian flu, an Influenza A subtype dubbed H5N1, is evolving a resistance to a group of antiviral drugs known as adamantanes, one of two classes of antiviral drugs used to prevent and treat flu symptoms, said CU-Boulder doctoral student Andrew Hill, lead study author. The rise of resistance to adamantanes -- which include the nonprescription drugs amantadine and rimantadane -- appears to be linked to Chinese farmers adding the drugs to chicken feed as a flu preventative, according to a 2008 paper by researchers from China Agricultural University, said Hill.

[Untitled] Study: Excessive use of antiviral drugs could aid deadly flu: The researchers also were able to demonstrate that the resistance developed as a result of natural selection, because the avian flu virus strains experienced mutations that changed the M2 protein to evade the drug more often than one would expect by chance. Sometimes, dramatic changes to the genetic code occur when diverse strains of viruses shuffle whole genes among themselves in a process called reassortment.

[Untitled] Bird Flu Monitor: Whatever happened to avian flu?: Bird Flu (Avian Flu, Avian Influenza): Most H5N1 viruses that have caused human illness and death appear to be resistant to amantadine and rimantadine, two antiviral medications commonly used for treatment of patients .

Vidyya Medical News Service: The researchers also were able to demonstrate that the resistance developed as a result of natural selection, because the avian flu virus strains experienced mutations that changed the M2 protein to evade the drug more often than one would expect by chance. Sometimes, dramatic changes to the genetic code occur when diverse strains of viruses shuffle whole genes among themselves in a process called reassortment.

[Untitled] GIS News:Google Earth tracks bird flu evolution: Its co-authors included CU-Boulder doctoral student Andrew Hill, CU-Boulder associate professor Robert Guralnick, recent CU-Boulder graduate Meredith Wilson, Farhat Habib of Kansas State University, and Daniel Janies of Ohio State University.

[Untitled] Bird flu becoming resistant to antiviral drugs: Bird flu becoming resistant to antiviral drugs. Posted by DrEddyClinic.com. January 9, 2009. New research suggests that bird, or avian, flu is becoming more resistant to antiviral drugs, so say researchers at the University of Colorado ...

[Untitled] Project Disaster » Blog Archive » More H5N1 Culling in India: “We got the reports Wednesday that confirmed that the dead birds had H5N1 virus,” Gupta said. About 31 000 poultry have already been culled at Matigara in Siliguri subdivision and Pubang in Takdah of .

[Untitled] Medical News and Health News Blog Medical Information » Blog ...: For the most part, substituting single genes from the 1918 virus onto the template of a much more benign contemporary virus yielded agents that could only replicate in the upper respiratory tract. One exception, however, included a complex of three genes that, acting in concert with another key gene, allowed the virus to efficiently colonize lung cells and make RNA polymerase, a protein necessary for the virus to reproduce.

[Prepared Citizens] Biosurveillance: Why A Head’s Up Approach Is Crucial To Saving ...: As of the July 25, 2008 FAO Avian Influenza Disease Emergency Situation Update, H5N1 pathogenicity is continuing to gradually rise in wild birds in endemic areas but the avian influenza disease situation in farmed birds is being held in check by vaccination.

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