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 [thepoultrysite - Industry News] BIRD FLU: H5N1 Detected in Vietnam; Bird Flu and US Government ...: GLOBAL - Summary of Bird Flu / Avian Influenza related news from across the world.

[Vietnam RSS News Feed by Intellasia.Net] Pitt scientists receive US$3.6m to test vaccine against deadliest ...: Unlike other avian flu vaccines, which are partially developed from live viruses, the vaccines Dr Ross and colleagues will test in non-human primates are based on a virus-like particle, or VLP, that is recognised by the immune system as a real virus but lacks genetic information to reproduce, making it a potentially safer alternative for a human vaccine. Given the evolving nature of H5N1, the vaccines have been engineered to encode genes for many influenza viral proteins to offer enhanced protection against possible new strains of the virus.

 [butner blogspot] CDC & NIH file patent, claim ownership of bird flu virus: According to sources, in a closed session at the WHO Interdisciplinary Working Group on Pandemic Influenza Preparedness, convened in Singapore from 31 July through 4 August 2007, the Director of the WHO Collaborating Centre at the US CDC stated to governments that the Centre had no interest in patents related to GISN materials. The Working Group meeting took place more than a year after the US CDC filed for patent related to the Indonesian, Thai, Hong Kong, and Korean H5N1 genes.

[Vietnam Health RSS News Feed by Intellasia.Net] DelSite files IND for nasal powder H5N1 (bird flu) influenza vaccine: The GelVac(tm) nasal powder is a novel, in-situ gelling powder based on DelSite's core technology, GelSite(r) polymer, which is a high molecular weight ionic polysaccharide manufactured under cGMP at kilogram scales. Based on this core technology, DelSite has developed three delivery platforms: GelVac(tm) nasal powder for nasal delivery of vaccines and therapeutics, GelSure(tm) for injectable delivery of therapeutics and GPDA(tm) depot adjuvant for injectable delivery of vaccines.

 [SLA Biomedical & Life Sciences Division Blog] H5N1: Update on Avian-to-Avian & Avian-to-Human FluTransmission ...: This bit of detective work has primarily used two pieces of evidence: Finding infected migratory birds and then tracking paths of infection along migratory flyways. The match up is good, although trucking of poultry infected by wildlife to cities that are not part of the migratory birds’ flyway can complicate the picture.

 [A Pandemic Chronicle] Clinical course details from China: National surveillance and laboratory testing might not have identified all H5N1 cases that occurred, especially if the cases were clinically mild. Clinical management was uncontrolled, H5N1 viral shedding data, immunological and pathological data were not available, and any differences in outcomes cannot be interpreted to be due to the use of antiviral drugs, corticosteroids, or other uncontrolled treatments.

[Latest Expert Blog Articles at http://www.healthedia.com] Vietnam: Local H5N1 vaccine shows promising early results: Excerpt:On August 21, at a meeting between officials of the Health Ministry and the Army Medical Institute, who conducted the H5N1 vaccine testing programme, the institute announced that the first phase of the testing programme had finished. The first 30 volunteers have shown good immunity.More than three months after they were injected with the second dose, doctors haven t recorded any side-effects in any volunteer.Doctors took blood samples from volunteers at different moments for testing which showed that the volunteers had str...

 [The Congress Blog] The Pentagon’s alarming project: Avian Flu Biowar Vaccine: On April 28 of this year in an official Press Release from Sanofi Pasteur US headquarters in Swiftwater, Pennsylvania and Lyon, France, the company stated, "Sanofi Pasteur, the vaccines division of Sanofi-Aventis Group, announced today that the US Department of Health and Human Services (HHS) has accepted H5N1 bulk vaccine antigen to produce approximately 38.5 million doses of vaccine to protect against a new strain of avian influenza. Sanofi Pasteur has a multi-year contract with HHS as part of its pandemic program, and will receive a payment of $192.5 million booked in the second quarter of 2008 for acceptance of the bulk vaccine lot."19

 [Health Blog] New Human H5N1 Bird Flu Vaccine From Baxter Shows Promise In Trial: Many experts believe it is only a matter of time before the deadly H5N1 bird flu virus mutates into a form that passes easily from human to human, making the possibiity of an H5N1 bird flu pandemic that would kill millions of people a major global public health priority. Hence the pressing need for a cost-effective vaccine that can be produced quickly to work against a number of divergent strains.

[Latest Expert Blog Articles at http://www.healthedia.com] Vietnam: Volunteers get second H5N1 vaccination: Via Thanh Nien Daily: Volunteers get second shot of bird flu vaccine.The Military Medical Academy in northern Ha Tay Province Saturday gave a second round of shots of a H5N1 vaccine to 30 volunteers.The volunteers were injected with a one millimeter dose as part of the second human trial of the vaccine, which began on April 19.Dr. Doan Huy Hau, head of the academy s epidemiology unit, said after 28 days, if the vaccine showed efficacy, the institute s researchers will suggest the Ministry of Health continue the trial with more volunteers.The trial vaccine, produced by the National Institut...

[Medical News and Health News Blog] Inovio Biomedical’s First Proprietary DNA Vaccine Achieves 100 ...: Only a broad-spectrum (heterologous) influenza DNA vaccine, such as the one we’re testing, would have the potential to provide protection against multiple known and unknown influenza strains. Our hope is that such a universal vaccine may one day replace the standard seasonal vaccine and provide protection against the generally inconvenient symptoms as well as the more severe effects, including death, that can result from seasonal and pandemic influenzas,”

 [Health and Wellness News from the Underground] Don't Believe the Hype about the Bird Flu Pandemic: In a nutshell: researchers identified survivors of the 1918 influenza pandemic, and then identified and cloned parts of their immune system called B-cells that produce antibodies that neutralize the 1918 virus.  Among other things, they hope to study the antibodies and the ways in which they neutralize the 1918 virus, in order to gain a better understanding of the way the human immune system might react to a pandemic H5 (or other) influenza virus.  The more we understand about these antibodies, the more easily we might be able to make vaccines and therapies for influenza viruses, and the safer these things will be.

[Weblog] Assessment of Current Situation: No evidence for genetic reassortment between human and avian influenza A virus genes has been heard discovered to date, and there is no evidence of any valuable unrest to escalating H5N1 virus strains to hint that greater transmissibility to or surrounded by humans. Genetic sequencing of avian influenza A (H5N1) viruses based on information from human tendencies in Vietnam, Thailand, and Indonesia indicates resistance to the antiviral medications amantadine and rimantadine, two of the medications commonly exhausted for service of influenza.

 [from the desk of Tim Blair NEWS & blog: Seattle, King County, Washington US.] abc: Results of mid-stage testing of the Baxter vaccine, Celvapan, showed two shots produced an immune response considered strong enough to protect 76 percent of healthy adults from both the H5N1 Vietnam strain it targets and the related Hong Kong strain; it appeared to protect 45 percent from a third, Indonesian strain.

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