Bird Flu Monitor > September 25, 2008
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[H5N1-links] Current vaccines for influenza provide protection against specific seasonal influenza A strains and their close relatives, but not against more distant seasonal influenza A viruses and new avian influenza A viruses, such as H5N1, .
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Some related posts from Technorati and Google.
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[Mystery Rays from Outer Space] Cross-protection against avian influenza?: It’s been shown several times that they do offer some protection, and in fact may be one reason that healthy adults are relatively resistant to influenza (the U-shaped curve above) — the very young would not have been previously exposed so wouldn’t have any cross-reactive T cells, while the very old often have defects in T cell responses.
[Journal of Clinical Investigation -- New Articles] Memory T cells established by seasonal human influenza A infection ...: In view of the 80%-90% amino acid sequence identity of these proteins between the avian and human type A strains, our data pertaining to the immunodominant protein regions recognized by healthy individuals of diverse HLA backgrounds could serve as a potent catalyst for such endeavors. For instance, the epitope regions we identified that frequently elicited highly cross-reactive CD4+ and CD8+ T cell responses merit special attention for the potential development of a universal vaccine that would generate or boost T cell responses against seasonal human influenza as well as avian influenza viruses.
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[H5N1-links] September 19, 2008: LOME, 18 September 2008 (IRIN) - Togo’s government has confirmed the H5N1 bird flu virus is responsible for the 10 September outbreak that killed 3500 birds .
[vaccine] Medicago gets big backer for tobacco vax: Medicago's virus-like particle technology produces recombinant vaccine antigens in non-transgenic plants. And the company has been touting the potential of the technology against an outbreak of H5N1 in humans.
[Medical Health Articles] New vaccine element could generate better protection from avian ...: Current vaccines for influenza provide protection against specific seasonal influenza A strains and their close relatives, but not against more distant seasonal influenza A viruses and new avian influenza A viruses, such as H5N1, which still poses a real global health concern. However, a team of researchers led by Tao Dong and Andrew McMichael, at Oxford University, United Kingdom, has now generated data that suggest adding a new component to vaccines for influenza might enable them to confer protection against a broad range of avian and seasonal influenza A viruses.
[MT Current Topics] Cdc Site On The Flu: Highly pathogenic H5N1 is deadly to domestic fowl, can be transmitted from birds to humans, and is deadly to humans. There is virtually no human immunity and human vaccine availability is very limited.
[Medical News and Health News Blog] Inovio Biomedicals First Proprietary DNA Vaccine Achieves 100 ...: Only a broad-spectrum (heterologous) influenza DNA vaccine, such as the one we’re testing, would have the potential to provide protection against multiple known and unknown influenza strains. Our hope is that such a universal vaccine may one day replace the standard seasonal vaccine and provide protection against the generally inconvenient symptoms as well as the more severe effects, including death, that can result from seasonal and pandemic influenzas,”
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[H5N1-links] September 15, 2008: Togo’s government is awaiting lab confirmation to learn if it was the H5N1 virus, which was first discovered in Togo in June 2007. The country’s livestock director, Komla Batasse Batawui, told IRIN that officials reacted as quickly as .
[10Sobak.com - Health & Beauty World Blog] Therapeutic DNA Vaccine Company Inovio Biomedical Reports Second ...: s proprietary electroporation delivery technology and, specifically, a new intradermal device, showed that 100% of immunized mice given a lethal challenge of highly pathogenic H5N1 influenza virus (A/Vietnam/1203/04) survived and showed only minor weight loss. These experimental universal vaccines are based on conserved genes common to multiple strains of seasonal influenza and even potential pandemic influenza, suggesting they may have the possibility to provide widespread protection against such viruses.
[Blog about Health] NanoViricides EKC Eye Drug Candidate Stopped Clinical ...: The Company is developing drugs against a number of viral diseases including H5N1 bird flu, seasonal influenza, HIV, EKC, hepatitis C, rabies, dengue fever, and Ebola virus, among others. This press release contains forward-looking .
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[Reason Magazine - All Reason Articles from the Past Year: Page 1] Which is Worse--Bird Flu or the Government's Reaction to Bird Flu?: I would argue that a self-interested government would have no other choice but to limit the export of vaccine in a true pandemic. In the case of a 1918-like deathathon, standing by their principles of private property would be a quick way to get overthrown (and shortly thereafter, the vaccines get seized anyway.) Of course, most governments would start restricting exports at death 1 because they're power-hungry hyper-douches.
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[temblors's Bulletins] Weaponized Avian Flu Intelligence Report: This is seriously flawed logic: seasonal flu vaccines have precious little effect against seasonal flu and NONE against the supposedly not-yet-pandemic variety of the H5N1 virus.. It is impossible to make a vaccine for a virus which .
[Men's & Drug's] Scientists Create First Successful Libraries of Avian Flu Virus ...: An international group of American and Turkish research scientists, led by Sea Lane Biotechnologies, has created the first comprehensive monoclonal antibody libraries against avian influenza (H5N1) using samples from survivors of the 2005/2006 “bird flu” outbreak in Turkey.These antibody libraries hold the promise for developing a therapy that could stop a pandemic in its tracks and provide treatment to those infected, as well as potentially pointing the way towards the development of a universal flu vaccine.
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